Proteinuria

What Does Proteinuria mean?

protein

Protein in the urine, also called proteinuria, means that the kidneys are allowing protein to leak into the urine instead of keeping it in the bloodstream where it belongs.
Small amounts may occur temporarily with dehydration, fever, or physical stress, but persistent proteinuria can be a sign of kidney disease.
Because protein loss can reflect damage to the kidney’s filtering system, identifying the cause early allows us to protect kidney function and prevent further damage.

Common Causes of Protein in the Urine (Proteinuria)

Protein in the urine may occur for several reasons, including:

  • Diabetes
    High blood sugar over time can damage the kidney’s filtering units.
  • High blood pressure
    Increased pressure can strain and damage the kidneys.
  • Kidney inflammation or disease
    Conditions that affect the kidney filters may allow protein to leak into the urine.
  • Temporary conditions
    Fever, dehydration, infections, stress, or heavy exercise can cause short-term proteinuria.
  • Certain medications
    Some medications may affect kidney function.
  • Autoimmune or systemic diseases
    Conditions that affect the immune system may involve the kidneys.
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How Is Proteinuria Evaluated?

To understand the cause and severity of proteinuria, your nephrologist may recommend:

  • Urine testing
    To measure the amount and type of protein being lost.
  • Blood tests
    To evaluate kidney function and look for underlying causes.
  • Blood pressure monitoring
    Since high blood pressure can worsen kidney damage.
  • Imaging studies
    Such as ultrasound, if structural concerns are suspected.
  • Kidney biopsy (in select cases)
    To identify specific kidney diseases when the diagnosis is unclear.

Early evaluation helps guide treatment and protect long-term kidney health.

Important NOTE

First Sign

Proteinuria can be the first sign of kidney disease. It also means that you officially have stage 1 CKD (even with a normal creatinine level!).

Risk Factor

It’s a risk factor for heart disease and mortality

Vascular Disease

Even teeny tiny amounts of albumin in urine increases the risk of a heart attack stroke, vascular disease and death

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concerns and take the next step toward better well-being.